Calibrum is an educational companion for adult men on testosterone replacement therapy. Most apps just log your injection. We do something different — we help you understand your labs, triage E2 symptoms, time your next bloodwork, and walk into your urology visit prepared.
What's inside
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AI Hormone Coach (24/7)
Wondering if your libido drop is high E2 or low SHBG? Just ask. Every reply is grounded in Endocrine Society guidelines, AUA clinical protocols, AAFP TRT monographs, Bhasin 2018, TRAVERSE trial, and FDA prescribing info — with citations.
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Lab Snap & Decode
Photograph your LabCorp or Quest PDF. AI extracts every marker — Total T, Free T, SHBG, E2, HCT, PSA — and shows them against your personal optimal range, not just generic "normal".
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E2 Symptom Triage
The most underserved part of TRT. Mood off? Joint pain? Water retention? AI pattern-matches your symptoms against high-E2 vs low-E2 vs unrelated profiles, based on your last lab.
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Free T Calculator (Free)
Vermeulen formula gold standard — Total T + SHBG + Albumin → Free T & Bioavailable T. No subscription required. Works pre-TRT for men investigating whether they're a candidate.
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Smart Bloodwork Timing
Changed your dose six weeks ago? Calibrum tells you exactly when E2 stabilizes (4–6 weeks for cypionate, 1–2 for daily SubQ) and reminds you to retest at the half-life-correct trough.
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Doctor Visit Prep
Auto-generated PDF before your appointment: 90 days of doses, lab trend, symptom log, and 3–5 prescriber-friendly questions tailored to your trajectory. Walk into urology prepared. Stop being dismissed.
E2 Symptom Triage — three honest verdicts
Log a side effect (libido, mood, joint pain, water retention, nipple sensitivity, dry skin, fatigue) and Calibrum shows a calibrated, conservative verdict based on the Endocrine Society guideline, AUA TRT guideline, and FDA prescribing information for testosterone and anastrozole:
🟢 Likely settling
Practical context from clinical guidelines, plus what to watch.
🟡 Worth flagging
Bring this up at your next visit — here are the questions to ask.
🔴 Stop & call your prescriber
Red flags: HCT > 55%, signs of DVT/PE, priapism, severe E2 crash — seek care now.
Built for every stage of TRT
- New TRT patients (months 1–6) — onboarding walks you through the first injection cycle, site rotation, and why week-3 anxiety isn't an emergency.
- Long-term users (6–24 months in) — past the honeymoon, deep in the "what-the-hell-is-happening" phase. Calibrum is calibrated for E2 management, HCT creep, and the SHBG / Free T puzzle.
- Telehealth TRT patients — Hone Health, Hims, Maximus Tribe, Marek Health, TRT Nation, Defy Medical protocols all supported. Calibrum is independent of all of them.
- Pre-TRT investigators ("Curious Carl") — start with the free Free T Calculator. No subscription needed.
How it compares
| Hone Health · telehealth TRT subscription | $1,884 / yr |
| Maximus Tribe · telehealth TRT subscription | $2,400 / yr |
| Endocrinologist visit · per appointment | $300–$500 |
| LabCorp panel · per draw | $50–$150 |
| Calibrum Premium · annual subscription | $49.99 / yr |
Calibrum is an educational companion. It does not prescribe testosterone or order labs. It coaches you through the 90% of TRT time when you're NOT at the clinic. You bring your own prescription and your own lab orders.
Calibrum Premium
Unlock AI Hormone Coach (Atlas), Lab Snap & Decode, E2 Symptom Triage, Smart Bloodwork Timing, Doctor Visit Prep PDF, and unlimited injection history.
- Weekly — $4.99 / week, with a 7-day free trial
- Annual — $49.99 / year (saves ~81% vs. weekly)
- Free Testosterone Calculator — free forever, no subscription
Auto-renews unless cancelled at least 24 hours before the end of the current period. Manage in Apple ID → Subscriptions. Prices may vary by region.
FAQ & Support
Privacy first
Injection logs, lab values, lab PDF photos, symptom entries, the Free T calculator, the Doctor Visit PDF, and your AI Coach chat history live on your device only. We never sell your data. We never share with advertising networks. The retrieval index that grounds the AI Coach runs on-device. See our Privacy Policy for the full architecture.
Disclaimer
Calibrum is an educational companion. It is not a medical device, does not prescribe medication, does not recommend dose changes, does not start or stop anastrozole, and does not diagnose conditions. Always consult your prescribing physician for medical decisions. Stop and seek emergency care for hematocrit greater than 55%, signs of deep-vein thrombosis or pulmonary embolism, priapism (painful erection > 4 hours), severe estradiol crash, or suicidal thoughts (US 988, UK Samaritans 116 123).